Benzamide derivatives as histone deacetylase inhibitors with potent differentiation and anti-proliferation activity
US7550490B2 · kind B2 · utility
11Cited by
1References
19Claims
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Key dates
| Filing date | Jul 11, 2007 |
| Grant date | Jun 23, 2009 |
| Priority date | — |
| Expiry date | Jul 11, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C237/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is related to the preparation and pharmaceutical use of novel benzamide derivatives as defined in the specification of formula (I) as histone deacetylase inhibitors (HDACI), their preparations and the methods of using these compounds or their pharmaceutically acceptable salt in the treatment of cell proliferative diseases, e.g. cancer and psoriasis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.