Hadron treatment planning with adequate biological weighting
US7550752B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 27, 2007 |
| Grant date | Jun 23, 2009 |
| Priority date | — |
| Expiry date | Dec 10, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2005/1087
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Treatment planning methods are provided that determine the variability of relative biological effectiveness (RBE) along a beam line and calculate, among other things, what intensity of hadron beam such as a proton or a carbon ion beam should be applied to achieve a desired biological dose at treatment site of a patient afflicted with a medical condition. Typically, three or four RBE values at three or four corresponding spacially-dispersed intervals along the beam line are calculated. In one embodiment, two RBE values for the spread-out Bragg peak (SOBP) region of the treatment site; one for the proximal section and one for the declining distal section is calculated. A third and different RBE value may be determined for the distal edge region of the SOBP. A fourth value may also be calculated for a pre-SOBP region.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.