Multivalent inhibitors of serum amyloid P component
US7553819B2 · kind B2 · utility
2Cited by
6References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 12, 2004 |
| Grant date | Jun 30, 2009 |
| Priority date | — |
| Expiry date | Oct 26, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel glycerol cyclic pyruvate derivates were prepared and demonstrated to inhibit the binding of an immobilized D-proline derivative to serum amyloid P component (SAP) have been prepared. As such, the compounds of the invention are useful for treating amyloidosis and diseases associated with amyloidosis, for example Alzheimer&supl;s disease and maturity onset diabetes mellitus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.