Cell permeable peptides for inhibition of inflammatory reactions and methods of use
US7553929B2 · kind B2 · utility
12Cited by
9References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 29, 2000 |
| Grant date | Jun 30, 2009 |
| Priority date | — |
| Expiry date | Dec 9, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the delivery of biologically active molecules, such as peptides, into the interior of cells by administering to the cells a complex comprising the molecule linked to an importation competent signal peptide. Such delivery can be utilized, for example, to treat and/or prevent inflammatory conditions, e.g., but not limited to, systemic inflammatory reactions such as endotoxic shock, localized inflammatory reactions such as inflammatory skin diseases and conditions, and inflammatory diseases such as autoimmune diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.