Specific antibodies for diagnosing heart failure
US7553937B2 · kind B2 · utility
13Cited by
5References
33Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Aug 7, 2003 |
| Grant date | Jun 30, 2009 |
| Priority date | — |
| Expiry date | Oct 1, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/34
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to an in vitro diagnosis of heart failure. More specifically, the invention relates to specific antibodies of a peptide domain which is situated on either side of hinge region R76S77 of proBNP(1-108). In particular, the invention relates to a method of obtaining the aforementioned antibodies and to the use thereof in detecting blood proBNP(1-108) with the exception of BNP(1-76) and BNP(77-108). The invention also relates to a method of detecting blood proBNP(1-108), reagents and a kit for same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.