Method for the use of [11C] carbon monoxide in labeling synthesis of 11C-labelled amides using metal amides and photo-induced free radical carbonylation
US7553942B2 · kind B2 · utility
4Cited by
0References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 7, 2005 |
| Grant date | Jun 30, 2009 |
| Priority date | — |
| Expiry date | May 13, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B59/002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using weakly nucleophilic amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.