Patent · US Active

Derivatives of 2-(iminomethyl)amino-phenyl, their preparation, their use as medicaments and the pharmaceutical compositions containing them

US7553976B2 · kind B2 · utility

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1Claims

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Assignee

Société de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S) SAS · FR

Inventors

Pierre-Etienne Chabrier de Lassauniere · Paris, FR
Serge Auvin · Mauchamps, FR
Dennis Bigg · Gif-sur-Yvette, FR
Michel Auquet · Palaiseau, FR
Jeremiah Harnett · Gif-sur-Yvette, FR

Key dates

Filing date	Jan 22, 2008
Grant date	Jun 30, 2009
Priority date	—
Expiry date	Jan 22, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/12
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to new derivatives of 2-(iminomethyl)amino-phenyl which are NO synthase inhibitors and can trap reactive oxygen species. These compounds can notably be used for the treatment of stroke, of neurodegenerative diseases and of ischemic or hemorragic cardiac of cerebral infarctions.These compounds include:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.