Patent · US Active

Nucleic acids encoding Candida kefyr cytosine deaminase

US7556955B2 · kind B2 · utility

0Cited by

0References

17Claims

0Family size

Assignee

Onyx Pharmaceuticals, Inc. · US

Inventors

Yuqiao Shen · Richmond, US
Sylvie Laquerre · King of Prussia, US
Amy M. Delaney · Belleville, US
Charles A. Omer · Waltham, US

Key dates

Filing date	Jul 20, 2006
Grant date	Jul 7, 2009
Priority date	—
Expiry date	Jan 23, 2027

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A new cytosine deaminase gene and protein from Candida kefyr are provided. This protein has increased ability to convert the 5-fluorocytosine prodrug to its toxic form when compared against the E. coli enzyme.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.