Patent · US Active

Optically active isomers of ketotifen and therapeutically active metabolites thereof

US7557128B2 · kind B2 · utility

12Cited by
5References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 30, 2007
Grant dateJul 7, 2009
Priority date
Expiry dateJun 19, 2027

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P37/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Racemic norketotifen, racemic 10-hydroxy-ketotifen, racemic 10-hydroxy-nor-ketotifen and optically active isomers of ketotifen, norketotifen, 10-hydroxy-ketotifen and 10-hydroxy-norketotifen were found to have antiallergic and anti-inflammatory effects while being devoid of the severe dose-limiting sedative side effects of Ketotifen.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.