Thyroid receptor ligands

US7557143B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Denis E. Ryono · Princeton, US
• Jon J. Hangeland · Levittown, US
• Todd J. Friends · Bordentown, US
• Tamara Dejneka · Skillman, US
• Pratik Devasthale · Plainsboro, US
• Yolanda Caringal · Lawrenceville, US
• Minsheng Zhang · Hackettstown, US
• Arthur M. P. Doweyko · Long Valley, US
• Johan Malm · Älta, SE
• Andrei Sanin · Kalmar, SE

Key dates

• Filing date: Apr 15, 2004
• Grant date: Jul 7, 2009
• Expiry date: Jan 28, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Thyroid receptor ligands are provided which have the general formula Iwherein: In addition, a method is provided for preventing, inhibiting or treating diseases or disorders associated with metabolism dysfunction or which are dependent upon the expression of a T3 regulated gene, wherein a compound as described above is administered in a therapeutically effective amount.