Stoichiometric conjugates of biocompatible polymers at the unpaired cysteine residue of the wild-type G-CSF
US7557195B2 · kind B2 · utility
4Cited by
10References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 20, 2003 |
| Grant date | Jul 7, 2009 |
| Priority date | — |
| Expiry date | Mar 23, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/535
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a conjugate of a biocompatible polymer and a G-CSF bonded through a thiol group of a dysteine residue in G-CSF at a 1:1 molar ratio, and methods of preparation thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.