Process for the synthesis of 3-(3-fluoro-4-hydroxyphenyl)-7-hydroxynaphthonitrile
US7557237B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Sep 1, 2004 |
| Grant date | Jul 7, 2009 |
| Priority date | — |
| Expiry date | Jul 25, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C255/53
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for making a compound of formula Iand intermediate compounds thereof, wherein R1 is CN, F or Cl; R2 is H or Br; and R3 and R4 are each independently H or F. The compounds of formula I are useful in the treatment of chronic inflammatory diseases, such as rheumatoid arthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.