System and method for irradiating a sample
US7558679B2 · kind B2 · utility
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Key dates
| Filing date | Oct 7, 2002 |
| Grant date | Jul 7, 2009 |
| Priority date | — |
| Expiry date | Apr 27, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/143333
- WIPO fieldEnvironmental technology
- WIPO sectorChemistry
Abstract
Method and system for footprinting a nucleic acid molecule. A sample consists of a nucleic acid molecule in an environment in which —OH radicals are generated when the environment is irradiated with an X-ray beam having an intensity less than 109 photons sec−1 mm−2 for an amount of time less than 1,000 msec. The sample is then irradiated with an X-ray beam having an intensity less than 109 photons sec−1 mm−2 for an amount of time less than 1,000 msec so as to generate —OH radicals in the environment. Fragmentation of the nucleic acid molecule is then detected.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.