Orodispersible dosage forms of desmopressin acetate

US7560429B2 · kind B2 · utility

Assignee

• Ferring B.V. · NL

Inventors

• Anders Nilsson · Västerås, SE
• Hans Lindner · Leichlingen, DE
• Jørgen Wittendorff · Copenhagen, DK

Key dates

• Filing date: May 7, 2003
• Grant date: Jul 14, 2009
• Expiry date: Jul 30, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/2095
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Good bioavailability of desmopressin can be obtained by means of an orodispersible pharmaceutical dosage form. Preferred dosage forms comprise desmopressin and an open matrix network which is an inert water-soluble or water-dispersible carrier material. Desmopressin formulated in this way is useful for voiding postponement, or the treatment or prevention of incontinence, primary nocturnal enuresis (PNE), nocturia or central diabetes insipidus. Peptides other than desmopressin can also be formulated in this way.