Methods of increasing delivery of active agents to brain comprising administering receptor associated protein (RAP) fragments conjugated to active agents
US7560431B2 · kind B2 · utility
10Cited by
19References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 12, 2005 |
| Grant date | Jul 14, 2009 |
| Priority date | — |
| Expiry date | Aug 12, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/23
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides compounds of conjugates of therapeutic or active agents with RAP or a RAP polypeptide, their pharmaceutical compositions and methods for using the such compounds and compositions in the diagnosis, prophylaxis, or treatment of diseases and conditions, including particularly diseases of the central nervous system or lysosomal storage diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.