Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions

US7560450B2 · kind B2 · utility

Assignee

• BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG · DE

Inventors

• Matthias Eckhardt · Hannover, DE
• Frank Himmelsbach · Mittelbiberach, DE
• Elke Langkopf · Biberach an der Riß, DE
• Roland Maier · Biberach an der Riß, DE
• Michael Mark · Biberach an der Riß, DE
• Mohammad Tadayyon · Hertford, GB

Key dates

• Filing date: Nov 18, 2003
• Grant date: Jul 14, 2009
• Expiry date: Feb 19, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D473/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to substituted xanthines of general formulathe tautomers, the stereoisomers, the mixtures thereof, the prodrugs thereof and the salts thereof, which have valuable pharmacological properties, particularly an inhibitory effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).