Patent · US Expired

Nucleic acid encoding dendritic cell co-stimulatory molecules

US7560540B2 · kind B2 · utility

35Cited by
6References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 24, 2006
Grant dateJul 14, 2009
Priority date
Expiry dateFeb 24, 2026

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.