Reshaped human antibody to human medulloblastoma cells
US7563599B2 · kind B2 · utility
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Key dates
| Filing date | May 6, 2004 |
| Grant date | Jul 21, 2009 |
| Priority date | — |
| Expiry date | Mar 2, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses reshaped antibody to human medulloblastoma cells comprising: Since the majority of this reshaped human antibody is derived from a human antibody and mouse CDRs have a low level of antigenicity, the reshaped human antibody of the present invention has a low level of antigenicity in humans, and is therefore expected to be useful as a therapeutic agent and diagnostic tool for brain tumors such as medulloblastoma which strongly express antigen that is recognized by this antibody.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.