Patent · US Active

Process for the preparation of diphenyl azetidinone derivatives

US7563888B2 · kind B2 · utility

1Cited by

0References

7Claims

0Family size

Assignee

Sanofi-Aventis Deutschland GMBH · DE

Inventors

Joachim-Heiner Jendralla · Frankfurt, DE
Guenter Billen · Frankfurt am Main, DE
Wendelin Frick · Bad Camberg, DE
Bernd Junker · Bad Soden, DE
Theodor Andreas Wollman · Hattersheim, DE

Key dates

Filing date	Nov 7, 2006
Grant date	Jul 21, 2009
Priority date	—
Expiry date	Nov 7, 2026

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is a process for the preparation of diphenylazetidinone derivatives of the formula (I) or forms thereof comprising the substituents X, R1 and/or R2 as defined herein. More specifically, the invention comprises methods for the preparation of these compounds by cyclization of certain β-amino carboxamides or β-amino carboxylic esters. These diphenylazetidinone compounds are useful in the treatment of high blood serum cholesterol levels and the maintenance of the reduced cholesterol levels achieved thereby.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.