Vacuum housing system for MALDI-TOF mass spectrometry
US7564028B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | May 1, 2007 |
| Grant date | Jul 21, 2009 |
| Priority date | — |
| Expiry date | Feb 29, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/24
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention is directed to ion source and vacuum housings for use in MALDI-TOF mass spectrometry which operates with any type of mass analyzer including linear, reflector, or tandem TOF-TOF instruments. By removing the requirement for the vacuum lock, the present invention allows operation of the ion source vacuum chamber at a pressure at least two orders of magnitude higher than conventional instruments. The present invention also requires only a single valve that isolates the ion source vacuum housing from the TOF analyzer vacuum housing. This is a significant improvement over vacuum locks in the art where the valve opening must be sufficiently large to allow the sample plate to pass through.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.