Activation of calcium-mediated cell functions in cells and tissues, including aggregation of human platelets. by nanosecond pulsed electric fields
US7565201B2 · kind B2 · utility
49Cited by
1References
25Claims
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Key dates
| Filing date | Dec 19, 2005 |
| Grant date | Jul 21, 2009 |
| Priority date | — |
| Expiry date | Oct 12, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/0424
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods for inducing calcium mobilization in cells through the application of nanosecond pulsed electric fields (“nsPEFs”) are provided. The invention also provides a method of increasing intracellular calcium in cells through the application of nsPEFs. In one embodiment of the invention, the cells are human platelets, whereby activation and aggregation of the platelets is induced. Methods for treating an injury, trauma, or loss of blood in a subject, through the application of nsPEFs are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.