Integrin targeted imaging agents
US7566442B2 · kind B2 · utility
1Cited by
14References
13Claims
0Family size
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Key dates
| Filing date | Jan 9, 2008 |
| Grant date | Jul 28, 2009 |
| Priority date | — |
| Expiry date | Jan 9, 2028 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Emulsions preferably of nanoparticles formed from high boiling liquid perfluorochemical substances, said particles coated with a lipid/surfactant coating are made specific to regions of activated endothelial cells by coupling said nanoparticles to a ligand specific for αvβ3 integrin, other than an antibody. The nanoparticles may further include biologically active agents, radionuclides, or other imaging agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.