1,3,4-Substituted pyrazoles as 5-HT receptor antagonists for the treatment of psychoses and neurological disorders

US7566709B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Kai Schiemann · Darmstadt, DE
• Oliver Schadt · Rodenbach, DE
• Christoph van Amsterdam · Darmstadt, DE
• Gerd Bartoszyk · Weiterstadt, DE
• Christoph Seyfried · Seeheim-Jugenheim, DE

Key dates

• Filing date: Mar 8, 2004
• Grant date: Jul 28, 2009
• Expiry date: Mar 8, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula (I) and salts and solvates thereof, in which X, R1, R2, R5 and Q have the meanings indicated in Claim 1, are suitable as ligands of 5 HT receptors; as well as intermediate compounds of the formula (IA).