2-pyridinyl-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one and 7-pyridinyl-2,3-dihydroimidazo[1,2-a] pyrimidin-5(1H)one derivatives
US7566720B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Aug 20, 2007 |
| Grant date | Jul 28, 2009 |
| Priority date | — |
| Expiry date | Aug 20, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to therapeutic uses of a pyrimidone derivative represented by formula (I) or a salt thereof:Wherein X, Y, R1, R2, m and n are as defined herein. Specifically, a medicament comprising the said derivative or a salt thereof as an active ingredient is used for preventive and/or therapeutic treatment of a neurodegenerative diseases caused by abnormal activity of GSK3β such as Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.