Diagnostic assays of secreted biological fluids for detection of infection and inflammatory conditions
US7569338B1 · kind B1 · utility
1Cited by
10References
10Claims
0Family size
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Key dates
| Filing date | Aug 25, 1999 |
| Grant date | Aug 4, 2009 |
| Priority date | — |
| Expiry date | Aug 25, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A rapid and convenient method for detecting inflammatory conditions in breast tissue, such as those associated with mastitis, is described. The method comprises measuring the presence and quantity of Serum Amyloid A (SAA) in milk samples obtained from the breast tissue. The amount of SAA present in the milk is positively correlated with the level of inflammation of the breast tissue, and can localize the inflammation to a particular region of the breast organ, such as a specific quadrant of a cow's udder. Test kits and their use in the method are also described.
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