Patent · US Expired

Polypeptide scaffolds and use thereof

US7569661B2 · kind B2 · utility

2Cited by

0References

12Claims

0Family size

Assignee

Modpro AB · SE

Inventors

Lars Baltzer · Uppsala, SE
Gunnar Dolphin · Bourg-de-Péage, FR
Bo Liedberg · Singapore, SG
Ingemar Lundstrom · Linköping, SE

Key dates

Filing date	Mar 26, 2003
Grant date	Aug 4, 2009
Priority date	—
Expiry date	Jan 19, 2024

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K17/00
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Novel peptide having a sequence according to SEQ. ID. No. 1, SEQ. ID. No. 2 and/or SEQ. ID. No. 3 are disclosed and also polypeptide scaffold consisting of a four helix bundle formed of two dimerized helix-loop-helix motifs, said helix-loop-helix motifs having sequences according to SEQ. ID. No. 1, SEQ. ID. No. 2 and/or SEQ. ID. No. 3 which may comprise a fluorescent probe at the side chain of Lys15 and a ligand with affinity for a target molecule at the side chain of Lys8 or Lys34.Also disclosed are polypeptide scaffolds for use in biosensing applications with or without the polypeptide scaffold anchored to a solid surface.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.