Substituted, bicyclic 8-pyrrolidinobenzimidazoles, methods for their production and their use as medicaments

US7569700B2 · kind B2 · utility

Assignee

• Sanofi-Aventis · FR

Inventors

• Elisabeth Defossa · Idstein, DE
• Karl Schoenafinger · Alzenau, DE
• Gerhard Jaehne · Frankfurt, DE
• Christian Buning · Frankfurt am Main, DE
• Georg Tschank · Frankfurt am Main, DE
• Ulrich Werner · Frankfurt am Main, DE

Key dates

• Filing date: Sep 14, 2007
• Grant date: Aug 4, 2009
• Expiry date: Sep 14, 2027

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to carboxamide derivative compounds of formula Iin which R1-R6 and R12 are hereinafter defined and together comprise carboximide derivatives for the therapeutic treatment of diabetes, hyperglycemia, lipid and carbohydrate metabolism disorders, arteriosclerotic manifestations and disorders and other blood sugar related disorders through a metabolic blood sugar-lowering action.