Binding proteins specific for human matriptase
US7572444B2 · kind B2 · utility
9Cited by
2References
17Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 16, 2005 |
| Grant date | Aug 11, 2009 |
| Priority date | — |
| Expiry date | Dec 16, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Binding proteins, such as fully human monoclonal antibodies and fragments thereof, directed to the antigen Matriptase and uses of such binding proteins are disclosed. Nucleotide sequences encoding, and amino acid sequences comprising heavy and light chain immunoglobulin molecules capable of binding to Matriptase are also disclosed. The invention also discloses cell lines expressing such immunoglobulin molecules and monoclonal antibodies to Matriptase. The antibodies can be used to detect, prevent, and treat diseases such as cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.