Biosyntheses of salinosporamide A and its analogs and related methods of making salinosporamide A and its analogs
US7572606B1 · kind B1 · utility
24Cited by
5References
18Claims
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Key dates
| Filing date | Sep 8, 2006 |
| Grant date | Aug 11, 2009 |
| Priority date | — |
| Expiry date | Jul 17, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/18
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed are methods of modulating biosynthesis of Salinosporamide A and its analogs, which are useful in treating cancer, inflammatory conditions, and/or infectious disease. The methods involve, for example, genetic manipulation, selection of reagents in the fermentation feedstock, and selection of fermentation conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.