Patent · US Active

Fibrin adhesive granulate and method for its preparation

US7572769B2 · kind B2 · utility

13Cited by

3References

24Claims

0Family size

Assignees

CSL Behring AG · DE
Glatt Process Technology GmbH · DE

Inventors

Mirna Rapp · Marburg, DE
Armin Prasch · Glückstadt, DE
Bernhard Luy · Glückstadt, DE

Key dates

Filing date	Jul 12, 2007
Grant date	Aug 11, 2009
Priority date	—
Expiry date	Feb 5, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K9/1611
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to a flowable fibrin adhesive granulate containing thrombin, Factor XIII, fibrinogen, and a calcium salt in the form of granules with a particle size of more than 50 μm to 1000 μm. Said granulate is useful for the healing of wounds in surgery, tissue therapy and/or as supporting material for biological factors. The invention also relates to an effervescent granulate and an effervescent powder for producing a foam that is suitable for hemostasis. The invention further relates to preparations to arrest bleeding containing a non-woven fabric for wounds consisting of a biodegradable supporting material that is coated with a fibrin glue granulate mixture or mixed granulate.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.