Therapeutic agents useful for treating pain

US7572812B2 · kind B2 · utility

Assignee

• Purdue Pharma, l.P., USA

Inventors

• Qun Sun · Princeton, US
• Kate Wen · Shanghai, CN
• Xiaoming Zhou · Plainsboro, US

Key dates

• Filing date: Jan 20, 2006
• Grant date: Aug 11, 2009
• Expiry date: Jul 10, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Piperidine Compounds; compositions comprising a Piperidine Compound; and methods for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal comprising administering to an animal in need thereof an effective amount of a Piperidine Compound are disclosed. In one embodiment, the Piperidine Compound has the formula:and pharmaceutically acceptable salts thereof, wherein Ar1, Ar2, X, R3, R4, and m are as disclosed herein.