Patent · US Expired

Indirubin derivatives having anticancer property against human cancer cell line

US7572923B2 · kind B2 · utility

3Cited by
0References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 26, 2005
Grant dateAug 11, 2009
Priority date
Expiry dateMay 2, 2025

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D209/40
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to an indirubin derivative having anticancer property by inhibiting cell proliferation as to human cancer cell line. More particularly, this invention provides the synthesis of indirubin derivative known as CDK(Cyclin-dependent kinase) inhibitor. Further, inhibition activity of proliferation as to human cancer cell line and apoptosis against induced-differentiation of said indirubin derivative are researched to develop a novel indirubin derivative having efficacious anticancer properties as to various human cell lines.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.