Spray drying process control of drying kinetics
US7575761B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 8, 2000 |
| Grant date | Aug 18, 2009 |
| Priority date | — |
| Expiry date | Jan 15, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1623
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides exemplary systems and methods for producing dry powder formulations. In one embodiment, a system (10) includes at least one conditioning zone (12) having an inlet (20) to introduce an atomized formulation (18) into the conditioning zone. A controller (14, 16) controls temperature and relative humidity of the airflow into the conditioning zone to allow amorphous-to-crystalline transformation of the atomized formulation. In another embodiment, the formulation is suspended in the conditioning zone for a residence time of sufficient duration to allow surface orientation of surface active components. A dryer (24) is coupled to the conditioning zone to dry the atomized formulation, and a collector (28) collects the formulation in powder form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.