Patent · US Expired

Screening method for identifying protective substances for treating neurodegenerative and/or ischemic disorders

US7575857B2 · kind B2 · utility

0Cited by

1References

10Claims

0Family size

Assignee

Sygnis Bioscience GmbH & Co. KG · DE

Inventors

Martin Maurer · Heidelberg, DE
Wolfgang Kuschinsky · Heidelberg, DE
Armin Schneider · Heidelberg, DE
Alfred Bach · Heidelberg, DE

Key dates

Filing date	Mar 14, 2003
Grant date	Aug 18, 2009
Priority date	—
Expiry date	Apr 26, 2023

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/28
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to a screening method for the identification of protective substances which influence haemoglobin formation in neuronal, myocardial and/or skeletomuscular cells, as well as to recombinant constructs, host cells and transgenic animals for the implementation of this method. In addition, the present invention relates to a diagnostic method for the differential diagnosis of neurodegenerative and/or ischaemic diseases in mammals and the use of haemoglobin, a globin or a mutein or fusion protein thereof or a corresponding nucleic acid for the treatment of neurodegenerative and/or ischaemic diseases in mammals. The invention furthermore relates to constructs for gene therapy of such diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.