Highly phosphorylated and sulfated recombinant factor IX
US7575897B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Mar 28, 2008 |
| Grant date | Aug 18, 2009 |
| Priority date | — |
| Expiry date | Mar 28, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a purified recombinant blood coagulation factor IX (rFIX) preparation, wherein at least 25% of the rFIX in the preparation is fully phosphorylated and sulfated, a cell culture expressing a rFIX resulting in said preparation, a pharmaceutical composition for treating a bleeding disorder comprising said preparation, and a method for treating a bleeding disorder comprising the step of administering said preparation to a patient in need thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.