Inhibition of adhesion and migration of an endothelial cell to fibronectin by neutrophil alpha-defensins
US7576060B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Jul 20, 2005 |
| Grant date | Aug 18, 2009 |
| Priority date | — |
| Expiry date | Jan 19, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/1709
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the inhibition of angiogenesis by neutrophil alpha-defensins. Further, the present invention relates to methods involving the inhibition of endothelial cell adhesion to the extracellular matrix, endothelial cell apoptosis, and endothelial cell angiogenesis.mediated by alpha-defensins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.