Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

US7576099B2 · kind B2 · utility

Assignee

• Renovis, Inc. · US

Inventors

• Michael G. Kelly · Thousand Oaks, US
• John Kincaid · Hayward, US
• Matthew Duncton · San Francisco, US
• Kiran Sahasrabudhe · San Diego, US
• Satyanarayana Janagani · Santa Clara, US
• Ravindra B. Upasani · San Jose, US
• Guoxian Wu · Palo Alto, US
• Zhi-Liang Wei · South San Francisco, US
• Carl Kaub · San Jose, US
• Yunfeng Fang · San Diego, US

Key dates

• Filing date: Feb 24, 2006
• Grant date: Aug 18, 2009
• Expiry date: Jun 18, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds are disclosed that have a formula represented by the following:The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.