Patent · US Active

Biaryl substituted nitrogen containing heterocycle inhibitors of LTA4H for treating inflammation

US7576102B2 · kind B2 · utility

0Cited by

3References

11Claims

0Family size

Assignee

deCode Genetics ehf · IS

Inventors

Vincent P. Sandanayaka · Marlborough, US
Jasbir Singh · Gilbertsville, US
Mahnaz Keyvan · Plainfield, US
Michael Krohn · Lorsch, DE
Mark E. Gurney · Grand Rapids, US

Key dates

Filing date	Aug 3, 2006
Grant date	Aug 18, 2009
Priority date	—
Expiry date	Aug 3, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D211/46
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention relates to a chemical genus of biaryl substituted nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula:They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.