Proteasome inhibitors and methods of using the same
US7576206B2 · kind B2 · utility
14Cited by
30References
1Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 12, 2004 |
| Grant date | Aug 18, 2009 |
| Priority date | — |
| Expiry date | Oct 14, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/025
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.