4-phenylpiperdine-pyrazole CCR1 antagonists
US7576218B2 · kind B2 · utility
2Cited by
2References
9Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 11, 2006 |
| Grant date | Aug 18, 2009 |
| Priority date | — |
| Expiry date | Oct 11, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally monocyclic and bicyclic compounds and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.