Noninvasive transdermal systems for detecting an analyte in a biological fluid and methods
US7577469B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Mar 11, 1999 |
| Grant date | Aug 18, 2009 |
| Priority date | — |
| Expiry date | Mar 11, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/8483
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to noninvasive transdermal systems comprised of a noninvasive transdermal patch and a reflectometer. The noninvasive transdermal patches are comprised of a wet chemistry component and a dry chemistry component. The wet chemistry component is a liquid transfer medium in the form of a gel layer for the extraction and liquid bridge transfer of the analyte of interest from the biological fluid within or beneath the skin to the dry chemistry component. The dry chemistry component is a reagent system for interacting with the analyte of interest (glucose) to generate a color change. The reflectometers include a modulated light source for emitting light to illuminate a target surface which possesses a certain color and shade of color for detection by an optical detector. The output signal is processed for determining a corresponding quantity or quality measurement.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.