Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using the same
US7579173B2 · kind B2 · utility
1Cited by
38References
28Claims
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Key dates
| Filing date | Jan 9, 2007 |
| Grant date | Aug 25, 2009 |
| Priority date | — |
| Expiry date | Jan 9, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to methodology for polymer grafting by a polysaccharide synthase and, more particularly, polymer grafting using the hyaluronate or chondroitin or heparin/heparosan synthases from Pasteurella, in order to create a variety of glycosaminoglycan oligosaccharides having a natural or chimeric or hybrid sugar structure with a targeted size that are substantially monodisperse in size.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.