Aligned scaffolds for improved myocardial regeneration
US7579189B2 · kind B2 · utility
30Cited by
1References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 29, 2008 |
| Grant date | Aug 25, 2009 |
| Priority date | — |
| Expiry date | Apr 29, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2535/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a biocompatible, three-dimensional scaffold useful to grow cells and to regenerate or repair tissue in predetermined orientations. The scaffold is particularly useful for regeneration and repair of cardiac tissue. The scaffold contains layers of alternating A-strips and S-strips, wherein the A-strips within each layer are aligned parallel to each other and preferentially promote cellular attachment over attachment to the S-strips. Methods of producing and implanting the scaffold are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.