Thia-tetraazaacenaphthylene kinase inhibitors

US7579356B2 · kind B2 · utility

Assignee

• Janssen Pharmaceuticals, Inc. · BE

Inventors

• Kathleen Battista · Williamstown, US
• Gilles Bignan · Bound Brook, US
• Peter J. Connolly · New Providence, US
• Stuart Hayden · Manalapan, US
• Sigmond Johnson · Flemington, US
• Ronghui Lin · Ambler, US
• Niranjan B. Pandey · White Marsh, US
• Mark Powell · Burlingame, US

Key dates

• Filing date: Apr 10, 2006
• Grant date: Aug 25, 2009
• Expiry date: Apr 10, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is directed to novel thia-tetraazaacenaphthylene compounds of Formula (I):and pharmaceutically acceptable forms thereof and their synthesis and use as inhibitors of ATP-protein kinase interactions.