Particles having an organized internal structure which are dispersed in an aqueous phase, the preparation thereof and use of same
US7579400B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 10, 2002 |
| Grant date | Aug 25, 2009 |
| Priority date | — |
| Expiry date | Dec 10, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2353/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to particles comprising: at least one ionically-charged water-soluble polymer; at least one surfactant having an ionic charge opposite to that of said polymer; and at least one water-soluble block copolymer having at least one non-ionic hydrophilic block and at least one non-ionic hydrophobic or ionic block. The invention also relates to a method of obtaining such particles consisting in: preparing a first aqueous mixture comprising the water-soluble, ionically-charged polymer and, if necessary, the water-soluble block copolymer if said copolymer has the same charge; subsequently, a second mixture is added to the above mixture, said second mixture comprising the surfactant and, if necessary, the water-soluble block copolymer if said copolymer has the same charge as the surfactant or if it is not ionically charged. Furthermore, the invention relates to the use of water-soluble block copolymers as an agent for stabilizing particles with a mesophase-forming internal structure, the internal structure of the resulting particles forming the same mesophase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.