Alleles of the zwf gene from coryneform bacteria

US7585650B2 · kind B2 · utility

Assignee

• Degussa AG · DE

Inventors

• Brigitte Bathe · Salzkotten, DE
• Natalie Schischka · Bielefeld, DE
• Georg Thierbach · Bielefeld, DE

Key dates

• Filing date: Apr 23, 2007
• Grant date: Sep 8, 2009
• Expiry date: Jun 2, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P13/227
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to mutants and alleles of the zwf gene of coryneform bacteria, which encode variants of the Zwf subunit of glucose 6-phosphate dehydrogenase (EC: 1.1.1.49), and to processes for preparing amino acids, in particular L-lysine and L-tryptophan, by using bacteria which harbor said alleles.