Patent · US Expired

GASP1: a follistatin domain containing protein

US7585835B2 · kind B2 · utility

88Cited by
20References
36Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 4, 2005
Grant dateSep 8, 2009
Priority date
Expiry dateJan 4, 2025

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/81
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to the use of a protein, GASP1, comprising at least one follistatin domain to modulate the level or activity of growth and differentiation factor-8 (GDF-8). More particularly, the invention relates to the use of GASP1 for treating disorders that are related to modulation of the level or activity of GDF-8. The invention is useful for treating muscular diseases and disorders, particularly those in which an increase in muscle tissue would be therapeutically beneficial. The invention is also useful for treating diseases and disorders related to metabolism, adipose tissue, and bone degeneration.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.