3′-prodrugs of 2′-deoxy-β-L-nucleosides
US7585851B2 · kind B2 · utility
26Cited by
35References
112Claims
0Family size
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Inventors
Key dates
| Filing date | Oct 25, 2004 |
| Grant date | Sep 8, 2009 |
| Priority date | — |
| Expiry date | Nov 29, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds, compositions and methods for the treatment of a host infected with a hepatitis B virus. Specifically, compound and compositions of 3′-esters of 2′-deoxy-β-L-pyrimidine nucleosides are disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents. Compound and compositions of 3′,5′-diesters of 2′-deoxy-β-L-pyrimidine nucleosides are also disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.