Substituted pyrazolo[3,4-D]pyrimidines as kinase antagonists
US7585868B2 · kind B2 · utility
98Cited by
46References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 4, 2007 |
| Grant date | Sep 8, 2009 |
| Priority date | — |
| Expiry date | Apr 4, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel compounds that can be used as antagonists of a lipid kinase such as a PI3 kinase, protein tyrosine kinase, and/or protein serine-threonine kinases such as mTOR. The present invention also provides methods of using the compounds for treating various disease conditions. The compounds include those having the formula:wherein the R1, R2 and R36 are as defined herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.