Metallic object with a nucleic acid coating and derivatives thereof and method for producing said object

US7585965B2 · kind B2 · utility

Assignee

• Technische Universitä{umlaut over ( )}t Dresden · DE

Inventors

• Dieter Scharnweber · Dresden, DE
• Rene Beutner · Dresden, DE
• Sophie Roessler · Dresden, DE
• Thomas Hanke · Veitshöchheim, DE
• Hartmut Worch · Dresden, DE
• Bernd Schwenzer · Rabenau, DE
• Jan Michael · Dresden, DE

Key dates

• Filing date: Jul 4, 2003
• Grant date: Sep 8, 2009
• Expiry date: Mar 9, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C40B40/06
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A metallic object has a coating made of a thin metal oxide layer and nucleic acids or nucleic acid derivatives bonded thereto. The nucleic acid compounds have 5′-terminal or 3′-terminal molecule areas that are incorporated stably into the metal oxide layer. The unincorporated areas of the nucleic acid compounds that are not incorporated into the metal oxide layer are freely accessible for subsequent interactions with other molecules such as complementary nucleic acids having active ingredients attached thereto.